Hypothesis
1. Chronic pain is a prevalent feature following combat trauma.
2. Post-amputation pain and neuropathic pain are major components of chronic pain following combat trauma.
Summary
This project builds on previous ADVANCE study Data Requests to:
1. Elucidate prevalence, impact and characteristics of chronic pain in the ADVANCE cohort.
2. Elucidate the prevalence of post-amputation pain as well as the impact and characteristics thereof in the ADVANCE cohort.
3. Elucidate the prevalence of chronic neuropathic pain as well as the impact and characteristics thereof in the ADVANCE cohort.
This will be a descriptive analysis of the current data. Average pain across the cohort as well as frequency of no pain (NRS=0), low pain (1-3), moderate pain (4-6), and high pain (>6) will be determined. The frequency of neuropathic pain using the DN4 will be determined. Demographics and comorbidities will be analysed with respect to groups of pain intensity and the presence or absence of neuropathic pain. The NPSI (Neuropathic Pain Symptom Inventory) will be used to categorise patients with neuropathic pain into three sensory phenotypes based on a recently suggested algorithm (Bouhassira, Pain, 2021). Demographics and comorbidities will be analysed with respect to these groups.
Keywords
Pain, Neuropathic Pain